Three measurement of enzyme activity on 24 patients. The measurements is of the enzymes sucrase and alkaline phosphatase. The interest is to compare the 'homogenate' and 'pellet' methods.
A data frame with 72 observations on the following 3 variables.
metha factor with levels SucHom
SucPel Alkphos, representing three different measurements,
i.e. homogenate and pellet values of sucrase, as well as homogenate values
of alkaline.
itema numeric vector, the person ID for the 24 patients
ya numeric vector, the measurements on the enzyme activity.
R. L. Carter; Restricted Maximum Likelihood Estimation of Bias and Reliability in the Comparison of Several Measuring Methods; Biometrics, Dec., 1981, Vol. 37, No. 4, pp. 733-741.
data(Enzyme)
Enzyme <- Meth( Enzyme )
#> The following variables from the dataframe
#> "Enzyme" are used as the Meth variables:
#> meth: meth
#> item: item
#> y: y
#> #Replicates
#> Method 1 #Items #Obs: 72 Values: min med max
#> SucHom 24 24 24 6.50 54.86 115.15
#> SucPel 24 24 24 18.87 135.65 331.50
#> Alkphos 24 24 24 7.21 121.97 231.89
summary( Enzyme )
#> #Replicates
#> Method 1 #Items #Obs: 72 Values: min med max
#> SucHom 24 24 24 6.50 54.86 115.15
#> SucPel 24 24 24 18.87 135.65 331.50
#> Alkphos 24 24 24 7.21 121.97 231.89
# plot( Enzyme )