Convert pharmacokinetic parameters for one compartment model

Calculate pharmacokinetic parameters with parameters (A and alpha) in one compartment model "Aexp(-alpha)"

Usage

OneComp_Coefficient_Exponent(A,alpha,A.sd=NA,alpha.sd=NA,
           covar=c(Aalpha=NA),...)

Arguments

A

parameter in one compartment model "Aexp(-alpha)"

alpha

parameter in one compartment model "Aexp(-alpha)"

A.sd

standard error of A

alpha.sd

standard error of alpha

covar

covariances among parameters

...

arguments to be passed to methods

References

http://www.nonmemcourse.com/convert.xls

Examples

OneComp_Coefficient_Exponent(A=0.125,alpha=0.5,A.sd=0.002,alpha.sd=0.009)
#>         Parameter Estimate    Std.err
#> Vdss         Vdss 8.000000 0.12800000
#> V1             V1 8.000000 0.12800000
#> Cl1           Cl1 4.000000 0.09633276
#> k10           k10 0.500000 0.00900000
#> alpha       alpha 0.500000 0.00900000
#> t_alpha   t_alpha 1.386294 0.02495330
#> True_A     True_A 0.125000 0.00200000
#> Frac_A     Frac_A 1.000000 0.00000000